Real pork wrapped around all natural American beefhide bones are a flavorful combination made with natural ingredients. These products are manufactured following strict Global Food Safety Initiative standards. Twistedz is also part of the Inspected, Tested, Safety (ITS) program, which gives customers access to independent testing data using the QR code on the packaging to offer transparency and confidence in our products. Disclaimer: Meant for intermittent usage. Select a chew large enough for your dog and supervise consumption. Discard any small pieces. Coatings are water-soluble but may stain indoor materials.